Ionis Pharmaceuticals Inc. (NASDAQ:IONS)

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  • wjj3: $IONS great looking chart
  • Eng_trader: @scottrades What do you think about $IONS here. Held up well last fri when the market pulled back and now pushing off the 8 EMA
  • scottrades: @Eng_trader $IONS Nice Daily chart. You'd want to use the 8/21EMAs as stops. Bit of a wide spread and hardly any volume so for today. I'd be small here.
  • DAN: $AVEO is also breaking out. Tickers from last night: Stocks on your hot list: $AMR -- Setting up really well. A jump to $160 puts it within 15% of 52-week high, which is important. $HAE $VRTX $UNM $NBIX $CECE -- Alert $9.90 $AVEO -- Alert $9.90 $IRDM $IONS -- Alert $47 $TXRH -- Target $110. Alert $95.00 $DINO $CEIX -- Alert $71.80
  • DAN: My Notes: SS 101322 COTD: Here’s your trade on Tesla ($TSLA) $SPY -- Big reversal. Bear markets don’t reward selling down gaps….or breakouts. $DIA -- short term double bottom. $QQQ -- Reversal Active Trade List: $TBT -- working. $TWNK -- buyable here. $LLY -- still stuck…but working. Stocks on your hot list: $AMR -- Setting up really well. A jump to $160 puts it within 15% of 52-week high, which is important. $HAE $VRTX $UNM $NBIX $CECE -- Alert $9.90 $AVEO -- Alert $9.90 $IRDM $IONS -- Alert $47 $TXRH -- Target $110. Alert $95.00 $DINO $CEIX -- Alert $71.80
  • DAN: ...
    $IONS (Biotech). 97 RS and making higher highs. Breakout on volume. Pivot was $46. Can’t chase up 7%. (Wait for it to come back. It will.) Very long base. “Cup” or “bowl”. Just a good capitulation in December, ...
  • steve71: $IBB $XBI XBI (small cap biotech) is up more today but IBB has the better chart overall. Is the market suggesting that recession is good for these names? Recession = Fewer rate hikes? $CLDX $VRTX Opening 10% positions in both today. $IONS My favorite biotech name is one of the few in the red today. Tracker only until it shapes up.
  • issues: @bRobert $ARKG $ARKK so which do you like better? I am buying ARKG since the chart is pointing up as in Break OUT! while ARKK is flat. I also like the lower price and the holdings. $ARKG is up (on the 3 month chart) 4.5% while ARKK is only 3.5%. The holdings for ARKG include: $TDOC $PACB $EXAS $REGN $VRTX $FATE $IONS $CDNA $TWST $VEEV. Holdings for $ARKK include: $TSLA $ROKU $TDOC $SQ $ZM $COIN $U $TWLO $SPOT Since we already own TSLA ROKU SQ ZM in ARKK, and don't own any of the holdings in ARKG we will buy ARKG. PS Look at the break outs in $PACB $REGN $FATE $IONS!! Powerful etf! with these big Break outs!
  • phgruver: @scottto_2 $LAKE $APPS $WKHS $BCLI $UPWK $VIVO $LPSN $QDEL $IONS $BNTX $BILL $MTCH $ZLAB #SpoutingHorn Don't get your hopes up too high. You are describing a "rising wedge" pattern, which usually leads to a bearish reversal. The declining rate of higher highs is counteracted with and increasing rate of higher lows as sellers don't wait as long to bail out.
  • gwenzee: @scottto_2 $LAKE $APPS $WKHS $BCLI $UPWK $VIVO $LPSN $QDEL $IONS $BNTX $BILL $MTCH $ZLAB #SpoutingHorn For the most part it looks like a Pop Out of the Box pattern. Stock rests in very tight range for minimum 4 days (no max) and then breaks out. Usually comes back to test break out area before on to "greatness." I have made some serious $$$ using this pattern. If you want to really learn more about it Google Pop Out of the Box trading and go to Webinar from Hit and Run Candlesticks,,,Rick Saddler.
  • scottto_2: ...
    $IONS - maybe getting there
    $BNTX
    $BILL- forming?
    $MTCH - maybe?
    $ZLAB - forming?

    Would love any feedback on this. Like i said, I'm sure there's millions of pages written about this somewhere I just wasn't aware of....
    Cheers.
  • issues: @scottto_2 $LAKE $APPS $WKHS $BCLI $UPWK $VIVO $LPSN $QDEL $IONS $BNTX $BILL $MTCH $ZLAB #SpoutingHorn Thanks for sharing your ideas. One question: do you own any of these? or just thinking about it?
  • Ava: @scottto_2 $LAKE $APPS $WKHS $BCLI $UPWK $VIVO $LPSN $QDEL $IONS $BNTX $BILL $MTCH $ZLAB #SpoutingHorn Looks like a nice discovery, thanks for sharing! having half of those "current possibilities" on my watchlist.
  • Ajax4Hire: @scottrades $IBB IBB iShares Nasdaq Biotechnology ETF 8.57% $AMGN - Amgen Inc 8.12% $GILD - Gilead Sciences Inc 7.55% $VRTX - Vertex Pharmaceuticals Inc 6.27% $ILMN - Illumina Inc 5.15% $BIIB - Biogen Inc 4.75% $REGN - Regeneron Pharmaceuticals Inc 3.47% $ALXN - Alexion Pharmaceuticals Inc 2.88% $SGEN - Seattle Genetics Inc 2.69% $INCY - Incyte Corp 1.95% $BMRN - Biomarin Pharmaceutical Inc 1.75% $ALNY - Alnylam Pharmaceuticals Inc 1.47% $NBIX - Neurocrine Biosciences Inc 1.28% $NVCR - Novocure Ltd 1.27% $MYL - Mylan NV 1.20% $IONS - Ionis Pharmaceuticals Inc 58.4% Top 15 holdings
  • Ajax4Hire: ...
    $ABT $ABUS $ACIA $ADRO $AEM $AFL $AGCO $AGX $AIG $ALGN $ALKS $ALL $AMP $AMT $ANAB $ANF $ANTM $AOBC $APA $APT $APYX $ASH $ASIX $AYI $BAX $BCRX $BEAT $BIDU $BIIB $BKD $BKNG $BLMN $BLOK $BMY $BOOM $CACC $CALA $CARS $CCI $CDE $CELG $CENT $CGEN $CHK $CLV ...
  • Aragorn: @Ajax4Hire $ABT $ABUS $ACIA $ADRO $AEM $AFL $AGCO $AGX $AIG $ALGN $ALKS $ALL $AMP $AMT $ANAB $ANF $ANTM $AOBC $APA $APT $APYX $ASH $ASIX $AYI $BAX $BCRX $BEAT $BIDU $BIIB $BKD $BKNG $BLMN $BLOK $BMY $BOOM $CACC $CALA $CARS $CCI $CDE $CELG $CENT $CGEN ...
  • Henry: @crank $IONS there are some barely intelligible tweets about a disappointing study
  • Herb: $IONS getting ripped. News, or jus the healthcare/biotech carnage of the week?
  • Robert1965: $IONS is one fire from $69 to ATH of 85.82 in less than a month
  • bRobert: $IONS Short squeeze. Flag trigger
  • woodman: @bRobert $IONS - It's been busy. It used to be $ISIS long ago, before that name became taboo.
  • bRobert: @woodman $IONS $ISIS Yes. Face lift, liposuction also
  • bRobert: $IONS . Mentioned a few days ago. spec biotech . . Earnings breakout. Flag with $30 target . Short squeeze possibility 20d to cover
  • bRobert: $IONS Flag $82 target with trigger
  • bRobert: $IONS Short squeeze day 2 17% 10d
  • traderbren: $IONS - constructive move in today's tape.
  • shoredriver: $IONS....down double digits due to joint liver drug not getting approval
  • traderbren: $IONS - moving into overhead gap. Long off the bottom.
  • Robert1965: @DAN $IONS your thoughts almost straight up since 10/2
  • DAN: @Robert1965 $IONS Doing well. Increasing volume. Two weeks to cover short positions. I'd stay with it...would protect the position with a stop below $60. Not a good place to buy for the reasons you mention -- gone straight up!
  • Robert1965: $IONS looking at this in the morning up to 63.20, looked like way over extend shorted at 60.95, last bump up 12:36, then down lower didn't break lower to 60.07, I am out now
  • Robert1965: $IONS in Bio tech up 2.05%, up from 58.37, last week 55.80, close yearly h 60.01
  • issues: @Robert1965 $IONS At resistance?
  • TRICIA: $IONS nhod ww
  • Bridget: #notes: Earnings after close or tomorrow morning: $STX $MCD $CAT $GOOGL $GM $AAOI - new high $BZUN - new high $WTW $NTRI - still working $JKS - flagging $CC - moving higher after flag $COHR $MOMO - higher volume $YY - chinese internet stocks up Breakouts: $PETS - on earnings $HON - after earnings $LITE - $VEEV - decent volume $NYT - ER on 7/27 $IONS $NXST $SBGI - starting to breakout IPOs $RETA - breakout and pullback $AKCS - still working, buy in the morning $BIVV - new high $RACE - working
  • Bridget: $IONS is breaking out higher
  • Robert1965: $IONS is up again $50.86, mentioned this at 47.78
  • Robert1965: $ions broke out yesterday from the base 47.78. up today to $50
  • Robert1965: $CZR looks like it has been trading in a range 12.00 to 12.60, for last several days, same with $IONS 47.77 to 49.23, anyone buying these, I tried but have missed them at or near the low, maybe consolidating
  • Robert1965: $IONS is making a move in the last 5 days looks like it is filling the gap, any opinions
  • spmeyers: @Robert1965 $IONS probably going up but not the greatest chart
  • Robert1965: $IONS anyone seeing why this is dropping, can't get to my Fidelity account to get news
  • jpmd349: @Robert1965 $IONS significant side effects from recent phase III drug trial
  • Robert1965: @jpmd349 $IONS Thanks
  • woodman: $IONS may be taking a breath before moving up some more. 5dEMA has been rough support.
  • woodman: $IONS $HA - both are flagging/ish. I bought a little of each today.
  • woodman: $IONS $BITA - both were on my list to buy yesterday and I nearly did right at the end of the day but decided to wait until today. Bummer!!
  • Robert1965: $IONS I posted on this a while back,, it looks like a breakoput
  • issues: @Robert1965 $IONS also $ABMD looks to be breaking out.
  • issues: @Robert1965 $IONS Did you buy any?
  • Aragorn: ...
    $IONS starting to accelerate above the 50
    $BEAT inside day and up keeps going IBD listed I think number one this week
    $CGNX - will try to make new all time highs soon
    $MZOR - watch this for how it reacts with the 8ema looking for this to bounce
    $SRP ...
  • Robert1965: $IONS question I STO covered call May 12 43.50, for $1.85, bid .55 ask 2.45, my ask 1.85, sold immediately what does that mean
  • Robert1965: @woodman $IONS I was thinking about shorting this yesterday, did you get out
  • shoredriver: $IONS $GS downgrades $25 price target...
  • Robert1965: $IONS I didn't add at below 49.57, still waiting for it to settle in.
  • Robert1965: $IONS looks like sell the news on the study, anyone going to add. I was thinking about adding below 49.57
  • traderbren: $YRD, $IONS -- looking good. Long.
  • woodman: @traderbren $YRD $IONS - I've been long this one as well. Earnings 3/15 amc.
  • Bridget: $IONS is continuing out higher from this breakout.
  • Bridget: Notes: Stocks needing to rest after yesterday's big rally. $CAT - down big on raid news $NVDA - breaking below $100 $WWW - breaking out of a W pattern on the weekly $NFLX - starting to break down from this squeeze Post Earnings moves: $TDOC - new 52 week high and making a nice cup pattern on the long term chart $GCP - pop on earnings and set new all time high. Holding for now $BURL - this retailer is at an all time high $MNST - pop on earnings but still holding below 200MA. $KO also up today $ADSW - day two out of this squeeze $IONS - running higher after 2 days of consolidation after pop $ACIW - closing at the HOD $KPTI and $NLNK - dumpster diving. Coming out of a very long base Momentum down: $IDCC $CRZO $STKL $TASR
  • Bridget: $IONS is breaking out of consolidation after earnings.
  • Bridget: Notes: $SPY - currently in sideways consolidation, will it resolve up or down? Healthcare $XRAY - moving higher out of recent consolidation in uptrend $NVS - in a smooth uptrend. Options are also rather liquid $ESPR - still working but this inverted hammer could be a top $AMGN - working $DVA - good entry here Utilities - XLU still moving up $WEC and $ETR breaking 200MA $AWK / $WTR - back above the 200MA, these could be a good long term play $CCI - gaining momentum $EBIX - breakout to her all time high on earnings, then slight pullback. Breakouts: $HTZ $ALJ $DK $WTW $IONS $ALB $LXU IPOs at all time highs $TTD $INVH $BIVV $ICHR
  • gwenzee: ...
    3) SPINRAZA - Spinal muscular atrophy - $IONS/$BIIB - First FDA approval in Dec. '16 - 750 K for 1st yr. and 375K / yr. after that.
    4) SEMAGLUTIDE - Diabetes- $NVO - Victoza is strongest daily dosage and Semaglutide is strongest weekly dosage.
    5 ...
  • shoredriver: $IONS up on lucrative deal with Novartis.....one of my all time fav biotechs
  • Robert1965: @champ $LABU $IONS $CLVS $UGAZ $ETE $BAC, sorry High of the Year
  • champ: @Robert1965 $LABU $IONS $CLVS $UGAZ $ETE $BAC..... YTDH
  • Robert1965: $IONS, up again to 51.55 to 53.07, anyone have the trial drug list that gives a schedule when drug tests are present, the site was given a while back but the link is no longer working
  • BocaRick: @Robert1965 $IONS Phase 3 6/30/2017 try. biopharmcatalyst.com/calendars
  • steve71: @Robert1965 $IONS https://www.clinicaltrials.gov/
  • Robert1965: @champ $LABU I don't know how I missed it was looking at $IONS, and $CLVS, checked it yesterday and missed the turn, today, got distracted with $UGAZ, and $ETE, did you get in today. Are you still holding $BAC that you that you bought before the HYR around 22.60,
  • champ: @Robert1965 $LABU $IONS $CLVS $UGAZ $ETE $BAC - Yes, I'm still holding $BAC...I sold 1/3 but I still have a good size position. Don't know what HYR means....?
  • issues: I just read a very encouraging article by Mike Brush (Brush Up On Stocks) from Market Watch: http://www.marketwatch.com/story/10-biotech-companies-ripe-for-a-buyout-courtesy-of-donald-trump-2016-11-17 The article is entitled "MW 10 Biotechcompanies Ripe for Buyouts Courtesy of Donald Trump". There are lots of reasons why a Trump administration is going to push biotechs up higher. The list for buyouts includes $BIIB $INCY $TSRO $IONS $MDCO $ACAD as buyout candidates. Others mentioned included $BMRN $AZN.LN. Finally the article said that with Prop 61 failing in the most liberal state (Cal) that would have limited drug prices, the biotechs can price in increases. Also mentioned JNJ MRK PFE. Nov/Dec biggest for biotech all year. Companies with drugs that have minimal competition include: $VRTX $SRPT $CELG $ALXN. We own $VRTX$ IONS $CELG $ALXN and $IBB
  • Robert1965: $ions Up again on earnings +22%
  • shoredriver: $IONS finally some good news....
  • woodman: $XBI - I had hoped it wouldn't be the case, but it's taking it on the chin today. Perhaps coincidentally occurring with $ALNY's collapse, but maybe not if folks are now skeptical on the entire RNAi platform. Too early to say that, though. But see $IONS, e.g.
  • issues: @woodman $XBI $ALNY $IONS Good points. We continue to patiently hold $IBB and $IONS. The product line and research in IONS looks great to me. We are long term holders of these. But the ones we are disappointed with (but still holding) are $GILD and $VRX $VRTX $JAZZ. Doing well with $CBPO and $ABMD. That $WBMD (also holding) seems like it's turning around.
  • woodman: $ALNY - bad news for this one. May affect all Rnai companies, including $ARWR $IONS ... http://endpts.com/deaths-force-alnylam-to-scrap-its-no-2-drug-in-phiii-development/
  • woodman: $ALNY $ARWR $IONS - I'm wondering if this will affect biotech tomorrow. $IONS is about 3% of $XBI.
  • woodman: @woodman $ALNY $ARWR $IONS $XBI - List of RNAi companies. Example 5,429 to make you wonder why we hold biotechs. Pass the smelling salts! http://biopharmguy.com/links/company-by-location-dna-rna.php http://biopharmguy.com/links/company-by-location-dna-rna.php
  • osgood: @woodman $ALNY $ARWR $IONS Amyloidosis (although it was primary AL, not the hereditary version) killed my best friend in 2010. It is an absolute killer disease.
  • Robert1965: $IONS Breaking out up 3.5%, +1.25
  • issues: @Robert1965 $IONS We hold this because we like the company and it's products. Our basis is $40. I am sure it will go back to $40 sometime...
  • Robert1965: $IONS Got stopped out the other day at 31.98, Now 35.60, is this the 3 day dump money or BIO Tech general up trend because of buyouts
  • Junior1: @Robert1965 @issues @DAN $IONS If you pull back and look at the Weekly chart, It's in a downward channel. Actually in a good spot here to short it. @DAN Any thoughts on this idea?
  • DAN: @Junior1 $IONS I see what you're seeing on the chart. A couple of thoughts -- very risky to short a biotech stock. Might work...but it's biotech, which rhymes with "financial wreck" If you are going to short, then consider waiting for a down day below the 200-day moving average, with a buy stop just above the 200-day moving average. Also...did I mention that it's a biotech stock? 8-)
  • Robert1965: $IONS This looks like it is breaking out?
  • shoredriver: $IONS....good news around partnership with $BIIB....
  • woodman: @shoredriver $IONS $BIIB I just starting buying $IONS last week, as posted. Unfortunately, I wanted to buy weeks ago on the crush down to $20 but didn't pull the trigger. I had a feeling it was an excellent opportunity. I usually regret not going with my gut feeling.
  • issues: @woodman $IBB $XBI Which ones did you buy? We hold just about all of them: $CELG $GILD $JAZZ, $VRTX $IONS (up huge today 35% MS drug working!)
  • woodman: @rj7150 $ARWR LOL! I don't have $ARWR but I did start a position in $IONS yesterday. Small but I'm ready for it to screw me over.
  • rj7150: @woodman $ARWR $IONS - What ever happened to Tekmar? I know it changed its name to hide the guilty. It saved me money on taxes!!
  • woodman: @rj7150 $ARWR $IONS Tekmira, formerly $TKMR, now $ABUS - as in run over by a-bus.. Great question. I stopped following it.
  • woodman: $IONS looks good. Against my own suggestion, I didn't buy it when it collapsed in late April. I even told someone (not here) it was one to buy and put in the desk drawer, but I didn't listen to myself. I entered today, about $8 after I should have bought it.
  • shoredriver: @woodman $GILD $SRPT, $IONS, $VRX, $VRTX, $BMRN.....and most of my various pos in $RLYP hoping like you that someone else hops in( still can't believe they took 32...was thinking 45 was first salvo.)..oh well....
  • issues: @jdurso $IONS Thanks for this explanation. You must be some kind of scientist, right? Anyway reports like yours make me more confident in holding the stock in IONS!! Many thanks to you!
  • issues: $IONS up 10% but I can''t figure out why. If you can understand this you're a better man than I am. And I have a degree in science. What is "antisense"? Is that the same as NONSENSE? Here's the news: Ionis Pharmaceuticals Announces Publication in Nature Biotechnology of a Novel Mechanism of Action for Antisense Drugs That Significantly Expands Therapeutic Opportunities..." What gibberish. Anyway we hold a position in this one that I hope will work back through the gap.
  • jdurso: @issues $IONS cant say understand but here is a definition Antisense: In molecular biology, the strand complementary to a coding sequence of a nucleic acid. Antisense DNA is the non-coding strand complementary to the coding strand in double-stranded DNA. The antisense strand serves as the template for messenger RNA (mRNA) synthesis. Antisense RNA is the non-coding strand complementary to a coding sequence of mRNA, a molecule involved in translating genetic instructions into proteins. Antisense RNA hybridizes with and inactivates mRNA. Antisense drugs are based on the fact that antisense RNA hybridizes with and inactivates mRNA. These drugs are short sequences of RNA that attach to mRNA and stop a particular gene from producing the protein for which it holds the recipe. Antisense drugs are being developed to treat lung cancer, diabetes and diseases such as arthritis and asthma with a major inflammatory component.
  • woodman: @jdurso $IONS I've met a lot of people who are antisense.
  • Marcelomex: @woodman $IONS good one
  • agent99: @jdurso $IONS Thanks for the explanation. Well done.
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Stock Price $42.45
Change 1.46%
Volume 731,441

Ionis Pharmaceuticals Inc is engaged in antisense drug discovery and development, exploiting a novel drug discovery platform it created to generate a broad pipeline of first-in-class drugs.

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